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Paxlovid cuts hospitalization, death only in COVID patients with weak immune systems -- Canadian study

 

...in JAMA Network Open, an observational Canadian study ties the antiviral drug combo nirmatrelvir-ritonavir (Paxlovid) to a lower risk of hospitalization or death only in very high-risk COVID-19 patients with weakened immune systems.

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Sepsis associated with COVID-19 infections higher among adults than previously realized-study

...in JAMA Network Open, researchers provide new evidence that the prevalence of SARS-CoV-2–associated sepsis among hospitalized adults is higher than previously thought, but deaths from the condition became less frequent as the pandemic progressed.

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It May Be Too Soon to Call It Covid Season

Why It's Too Soon to Call It Covid Season | WIRED

...experts on the front lines and doing data analysis say it’s too soon to declare that Covid has achieved seasonality. Looking back over the previous three years, they do see patterns: a spike at some point in the summer, such as the arrival of the Delta variant in 2021, and a spike sometime in the late fall or winter, such as the Thanksgiving surge of Omicron later that year. But those spikes haven’t occurred at the exact same time from year to year, and it’s possible they didn’t all arise for the same reasons.

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Patients with long Covid may be at increased risk for heart problems for a year after infection--study

Patients with coronavirus disease 2019 (COVID-19) present increased risk for ischemic cardiovascular complications up to 1 year after infection. Although the systemic inflammatory response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection likely contributes to this increased cardiovascular risk, whether SARS-CoV-2 directly infects the coronary vasculature and attendant atherosclerotic plaques remains unknown.

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During the Delta wave, COVID patients were at higher risk of new cardiovascular, cerebrovascular conditions --study

A large study from Singapore suggests that COVID-19 infection increased the risk of new-onset cardiovascular and cerebrovascular complications during the Delta variant era and that vaccination lowered the risk.

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Main US COVID markers mixed bag; main ones show slight rise, two indicate decline

US COVID-19 hospitalizations and deaths continued their slow rise over the past week, but two early indicators showed declines, the Centers for Disease Control and Prevention (CDC) said in its latest data update.

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